New telephone numbers:
Office: +36 30 427 6251 / Sequencing Lab: +36 30 427 6152 / Food Safety Lab: +36 30 392 4192 / Animal Health Lab: +36 30 392 3642
Déri S, Borbás J, Hartai T, Hategan L, Csányi B, Visnyovszki Á, Madácsy T, Maléth J, Hegedűs Z, Nagy I, Arora R, Labro AJ, Környei L, Varró A, Sepp R, Ördög B. Impaired cytoplasmic domain interactions cause co-assembly defect and loss of function in the p.Glu293Lys KNCJ2 variant isolated from an Andersen-Tawil Syndrome patient. Cardiovasc Res. 2020
Recent paper: The Role of MicroRNAs upon Epithelial-to-Mesenchymal Transition in Inflammatory Bowel Disease
Cells 2019, 8 (11), 1461

Éva Boros, István Nagy: The Role of MicroRNAs upon Epithelial-to-Mesenchymal...

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Recent paper:Y-chromosome haplogroups from Hun, Avar and conquering Hungarian period nomadic people of the Carpathian Basin
Sci Rep 9, 16569 (2019) doi:10.1038/s41598-019-53105-5

Endre Neparáczki, Zoltán Maróti, Tibor Kalmár, Kitti Maár, István Nagy, Dóra Latinovics, Ágnes Kustár, György Pálfi, Erika Molnár, Antónia...

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Recent paper: Clinical and genetic landscape of treatment naive cervical cancer: Alterations in PIK3CA and in epigenetic modulators associated with sub-optimal outcome
EBioMedicine. 2019 Apr 2. pii: S2352-3964(19)30214-2.

Scholl S, Popovic M, de la Rochefordiere A, Girard E, Dureau S, Mandic A, Koprivsek K, Samet N, Craina M, Margan M, Samuels S, Zijlmans H,...

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Recent paper: CRISPR-interference based modulation of mobile genetic elements in bacteria
Synthetic Biology, https://doi.org/10.1093/synbio/ysz008

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Recent paper: Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiota
Bálint Kintses, Orsolya Méhi, Eszter Ari, Mónika Számel, Ádám Györkei, Pramod K. Jangir, István Nagy, Ferenc Pál, Gergely Fekete, Roland Tengölics, Ákos Nyerges, István Likó, Anita Bálint, Tamás Molnár, Balázs Bálint, Bálint Márk Vásárhelyi, Misshelle Bustamante, Balázs Papp & Csaba Pál. Nature Microbiology volume 4, pages 447–458 (2019)

Bálint Kintses, Orsolya Méhi, Eszter Ari, Mónika Számel, Ádám...

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Recent paper: Draft Genome Sequence of Propionibacterium acnes subsp. elongatum Strain Asn12
Microbiol Resour Announc 7:e00801-18.

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Metagenomics de novo assembly

Next-generation sequencing techniques allow us to generate reads from a microbial environment in order to analyze the microbial community. However, assembling of a set of mixed reads from different species to form contigs is a bottleneck of metagenomic research. Although there are many assemblers for assembling reads from a single genome, there are few assemblers for assembling reads in metagenomic data without reference genome sequences. Moreover, the performances of these assemblers on metagenomic data are far from satisfactory, because of the existence of common regions in the genomes of subspecies and species, which make the assembly problem much more complicated. To solve this problem we use the latest, best benchmarked algorithms for assembling reads in metagenomic data, which contain multiple genomes from different species.

 

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